diff --git a/CMakeLists.txt b/CMakeLists.txt
index 1197251dd..1cfd610f9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -21,6 +21,7 @@ option(IMHEX_REPLACE_DWARF_WITH_PDB     "Remove DWARF information from binaries
 option(IMHEX_ENABLE_STD_ASSERTS         "Enable debug asserts in the C++ std library. (Breaks Plugin ABI!)"                     OFF)
 option(IMHEX_ENABLE_UNIT_TESTS          "Enable building unit tests"                                                            OFF)
 option(IMHEX_ENABLE_PRECOMPILED_HEADERS "Enable precompiled headers"                                                            OFF)
+option(IMHEX_COMPRESS_DEBUG_INFO "Compress debug information"                                                                   ON )
 
 set(IMHEX_BASE_FOLDER "${CMAKE_CURRENT_SOURCE_DIR}")
 set(CMAKE_MODULE_PATH "${IMHEX_BASE_FOLDER}/cmake/modules")
diff --git a/cmake/build_helpers.cmake b/cmake/build_helpers.cmake
index e0eacd9db..2df604b7d 100644
--- a/cmake/build_helpers.cmake
+++ b/cmake/build_helpers.cmake
@@ -531,6 +531,31 @@ function(downloadImHexPatternsFiles dest)
 
 endfunction()
 
+# Compress debug info. See https://github.com/WerWolv/ImHex/issues/1714 for relevant problem
+macro(setupDebugCompressionFlag)
+    include(CheckCXXCompilerFlag)
+    include(CheckLinkerFlag)
+
+    check_cxx_compiler_flag(-gz=zstd ZSTD_AVAILABLE_COMPILER)
+    check_linker_flag(CXX -gz=zstd ZSTD_AVAILABLE_LINKER)
+    check_cxx_compiler_flag(-gz COMPRESS_AVAILABLE_COMPILER)
+    check_linker_flag(CXX -gz COMPRESS_AVAILABLE_LINKER)
+
+    if (NOT DEBUG_COMPRESSION_FLAG) # Cache variable
+        if (ZSTD_AVAILABLE_COMPILER AND ZSTD_AVAILABLE_LINKER)
+            message("Using Zstd compression for debug info because both compiler and linker support it")
+            set(DEBUG_COMPRESSION_FLAG "-gz=zstd" CACHE STRING "Cache to use for debug info compression")
+        elseif (COMPRESS_AVAILABLE_COMPILER AND COMPRESS_AVAILABLE_LINKER)
+            message("Using default compression for debug info because both compiler and linker support it")
+            set(DEBUG_COMPRESSION_FLAG "-gz" CACHE STRING "Cache to use for debug info compression")
+        else()
+            message("No compression available for debug info")
+        endif()
+    endif()
+
+    set(IMHEX_COMMON_FLAGS "${IMHEX_COMMON_FLAGS} ${DEBUG_COMPRESSION_FLAG}")
+endmacro()
+
 macro(setupCompilerFlags target)
     # IMHEX_COMMON_FLAGS: flags common for C, C++, Objective C, etc.. compilers
 
@@ -566,6 +591,10 @@ macro(setupCompilerFlags target)
         set(IMHEX_C_CXX_FLAGS "${IMHEX_C_CXX_FLAGS} -pthread -Wno-dollar-in-identifier-extension -Wno-pthreads-mem-growth")
     endif ()
 
+    if (IMHEX_COMPRESS_DEBUG_INFO)
+        setupDebugCompressionFlag()
+    endif()
+
     # Set actual CMake flags
     set_target_properties(${target} PROPERTIES COMPILE_FLAGS "${IMHEX_COMMON_FLAGS} ${IMHEX_C_CXX_FLAGS}")
     set(CMAKE_C_FLAGS    "${CMAKE_C_FLAGS}    ${IMHEX_COMMON_FLAGS} ${IMHEX_C_CXX_FLAGS}")
diff --git a/dist/web/Dockerfile b/dist/web/Dockerfile
index 9306b0009..a8198a23d 100644
--- a/dist/web/Dockerfile
+++ b/dist/web/Dockerfile
@@ -59,6 +59,7 @@ cmake /imhex
     -DIMHEX_OFFLINE_BUILD=ON                                                                            \
     -DIMHEX_STATIC_LINK_PLUGINS=ON                                                                      \
     -DIMHEX_EXCLUDE_PLUGINS="script_loader"                                                             \
+    -DIMHEX_COMPRESS_DEBUG_INFO=OFF                                                                     \
     -DNATIVE_CMAKE_C_COMPILER=gcc                                                                       \
     -DNATIVE_CMAKE_CXX_COMPILER=g++                                                                     \
     -DCMAKE_C_COMPILER_LAUNCHER=ccache                                                                  \